Crestone currently is home to the following businesses:
- Architectural Harmonics-110 N. Alder St.
- Arwen Technologies LLC-116 S. Alder St., Suite D2
- Aventa Credit Union-110 E. Silver Ave.
- Bliss Inn-187 W. Silver Ave.
- Blue Earth Design-420 E. Galena Ave.
- Bugling Bull Taxidermy-(719) 256-4235
- Cloud Station-222 S. Cottonwood St.
- Crestone Acupuncture-(303) 332-3520
- Crestone Artisans Gallery-120 S. Cottonwood St.
- Crestone Casitas Self Storage-160 E. Silver Ave.
- Crestone Computer-116 S. Alder St., Suite D
- Crestone Eagle-180 W. Galena Ave.
- Crestone Hardware-191 E. Galena Ave.
- Crestone Inn-171 S. Alder St.
- Crestone Mercantile Grocery-182 E. Galena Ave.
- Crestone Oasis-(719) 256-5445
- Crestone Spirits Center-158 E. Silver Ave.
- Elephant Cloud Market-200 S. Cottonwood St.
- Higher Elevation-152 W. Silver Ave.
- One Earth One Body LLC-(719) 937-7684
- Our Food is Art/Taco Love-121 E. Galena Ave.
- Ragpicker Books-213 E. Golden Ave.
Sacred Spirit Lightwork-116 S. Alder St., Suite C
- Sangre de Cristo Real Estate-116 S. Alder St., Suite A
- Shakti Sharanam-308 E. Golden Ave.
- Shangrilah Colorado LLC-259 S. Cottonwood St.
- Sun Studio-(719) 937-7694
Area Hot Springs:
- Joyful Journey Hot Springs
- Sand Dunes Swimming Pool
- Valley View Hot Springs